Module manager: Dr Glyn Hemsworth
Email: G.R.Hemsworth@leeds.ac.uk
Taught: Semester 1 (Sep to Jan) View Timetable
Year running 2023/24
| BLGY1115 | Introduction to Cell Biology: from Molecules to Cells and Ti |
| FOBS1135 | The Basis of Life |
This module is not approved as a discovery module
Living cells are able to perform a huge variety of different and complex functions, yet 99% of their mass is made up of just common 6 elements.
This module will cover areas of Chemistry that are of direct relevance to the understanding of biological processes and provide an understanding of how simple inorganic elements are organised into the large macromolecular structures and polymers (nucleic acids, proteins, polysaccharides and lipids) that are crucial for life.
The importance of chemical structure in determining biological roles is a key theme. You will study the properties and kinetics of enzymes, the biological catalysts that control metabolic processes, and how those metabolic processes provide cells with the energy needed for life.
On completion of this module, students should be able to demonstrate a good understanding of:
1. The basic concepts of chemistry and how this helps us understand the structures and functions of the principal macromolecules of cells including proteins and an introduction to enzymes.
2. How the structures of carbohydrates and lipids relate to their major functions;
3. The structures of DNA and RNA, and the enzymology of aspects of their replication, transcription and translation.
4. Energy metabolism and adaptive processes to optimise the use of biomass or other energy sources from a cellular perspective.
This course will provide the core concepts central to biochemistry, covered by two central themes:
1. Molecules of life
2. Energy & Metabolism
- Cell chemistry. functional groups, bonding and macromolecules
- Lipids and membranes
- Sugars and polysaccharides
- Amino acids and proteins, protein structure and function, protein folding and disease
- Enzymes, introduction to basic thermodynamics, substrate binding and catalysis, enzyme kinetics and measuring reaction rates.
- Nucleic acids and the central dogma
- DNA Replication, genome organization and DNA repair
- RNA, transcription and non-coding RNA, differences between prokaryote/eukaryote translation, introduction to post-translational modification
- Introduction to metabolism and fatty acids
- Glycolysis and the TCA cycle
- Oxidative phosphorylation
- Nitrogen metabolism and amino acid synthesis
- Photosynthesis
| Delivery type | Number | Length hours | Student hours |
|---|---|---|---|
| Lecture | 22 | 1 | 22 |
| Independent online learning hours | 30 | ||
| Private study hours | 48 | ||
| Total Contact hours | 22 | ||
| Total hours (100hr per 10 credits) | 100 | ||
48 hours of private study.
- Student attendance at lectures will be monitored in line with standard faculty practice. Synchronous online delivery via Blackboard Collaborate.
- Completion of MRQs tests.
- Engagement with VLE resources.
- voluntary drop-in sessions.
| Assessment type | Notes | % of formal assessment |
|---|---|---|
| In-course MCQ | 30 min MRQ test (to be completed in a single attempt within a 24 hour time-frame, restricted to a defined duration once the test starts). | 50 |
| In-course MCQ | 30 min MRQ test (to be completed in a single attempt within a 24 hour time-frame, restricted to a defined duration once the test starts). | 50 |
| Total percentage (Assessment Coursework) | 100 | |
Further guidance on the assessment will be provided in Minerva.
The reading list is available from the Library website
Last updated: 4/28/2023
Errors, omissions, failed links etc should be notified to the Catalogue Team